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. 2021 Jun;10(6):1941–1950. doi: 10.21037/gs-21-19

Figure 4.

Figure 4

The upstream miRNA of KIF23 in TNBC cells. (A) Venn diagram of miRNAs target on KIF23 mRNA based on targetscan, miRDB, Tarbase and starbase. (B) Western blot assays indicate miR-195-5p inhibits expression of KIF23 in TNBC cells. (C) A schematic representation of the interaction between miR-195-5p and KIF23 3'UTR. (D) Dual luciferase reporter assay of miR-195-5p and KIF23 3'UTR in 293T cells. (E) Colony formation assays and transwell assays (×100) indicate miR-195-5p inhibits proliferation and migration of TNBC cells. ns, P>0.05, **P<0.01, ***P<0.001. All experiments were repeated three times.