Table 4.
Simulation scenario | Assumed probability of DLT | Accuracy index AN |
Probability of correctly selecting MTD | Mean proportion above MTD | Mean proportion within one dose of MTD | Mean number treated | ||||
---|---|---|---|---|---|---|---|---|---|---|
Dose level | ||||||||||
1 | 2 | 3 | 4 | 5 | ||||||
1 | 0.14 | 0.23 | 0.35 | 0.47 | 0.57 | 0.91 | 0.50 | 0.22 | 0.95 | 19.7 |
2 | 0.35 | 0.40 | 0.50 | 0.60 | 0.70 | 0.93 | 0.36 | 0.83 | 0.67 | 18.4 |
3 | 0.15 | 0.35 | 0.40 | 0.50 | 0.60 | 0.92 | 0.45 | 0.46 | 0.88 | 19.3 |
4 | 0.05 | 0.15 | 0.35 | 0.50 | 0.60 | 0.93 | 0.62 | 0.25 | 0.97 | 20.1 |
5 | 0.05 | 0.15 | 0.25 | 0.35 | 0.60 | 0.92 | 0.50 | 0.08 | 0.78 | 20.0 |
6 | 0.05 | 0.10 | 0.20 | 0.30 | 0.35 | 0.93 | 0.34 | 0.00 | 0.53 | 20.2 |