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. 2021 Jul 6;22:433. doi: 10.1186/s13063-021-05384-5

Table 4.

Performance measures for simulated trials

Simulation scenario Assumed probability of DLT Accuracy index
AN
Probability of correctly selecting MTD Mean proportion above MTD Mean proportion within one dose of MTD Mean number treated
Dose level
1 2 3 4 5
1 0.14 0.23 0.35 0.47 0.57 0.91 0.50 0.22 0.95 19.7
2 0.35 0.40 0.50 0.60 0.70 0.93 0.36 0.83 0.67 18.4
3 0.15 0.35 0.40 0.50 0.60 0.92 0.45 0.46 0.88 19.3
4 0.05 0.15 0.35 0.50 0.60 0.93 0.62 0.25 0.97 20.1
5 0.05 0.15 0.25 0.35 0.60 0.92 0.50 0.08 0.78 20.0
6 0.05 0.10 0.20 0.30 0.35 0.93 0.34 0.00 0.53 20.2