TABLE 2.
Model 1 (n = 9716) | Model 2 (n = 8061) | Model 3 (n = 4098) | ||||
---|---|---|---|---|---|---|
β | p value | β | p value | β | p value | |
Age (10 years) | 0.042 | .001 | 0.025 | .070 | 0.072 | <.001 |
Male sex | 0.019 | .056 | 0.020 | .070 | 0.009 | 0.557 |
Current smoking | 0.061 | <.001 | 0.052 | <.001 | 0.067 | <.001 |
Hypertension | −0.001 | 0.962 | 0.006 | 0.655 | 0.018 | 0.372 |
Diabetes | 0.061 | <.001 | 0.053 | <.001 | 0.072 | <.001 |
Hyperlipidemia | 0.029 | 0.567 | 0.037 | 0.514 | 0.211 | .011 |
eGFR | −0.075 | <.001 | −0.053 | <.001 | −0.033 | .070 |
Heart failure | 0.025 | .016 | ‐ | ‐ | 0.015 | 0.347 |
Previous stroke | 0.001 | 0.928 | −0.006 | 0.615 | −0.009 | 0.560 |
PAD | 0.056 | <.001 | 0.068 | <.001 | 0.069 | <.001 |
COPD | 0.103 | <.001 | 0.090 | <.001 | 0.122 | <.001 |
Previous/present cancer | 0.030 | .003 | 0.030 | .006 | 0.046 | .002 |
Dementia | −0.010 | 0.288 | −0.002 | 0.835 | −0.014 | 0.351 |
Atrial fibrillation | 0.042 | <.001 | 0.040 | .001 | 0.043 | .009 |
LVEF | ‐ | ‐ | 0.115 | <.001 | ‐ | ‐ |
hs‐cTnT (ln) | ‐ | ‐ | ‐ | ‐ | 0.111 | <.001 |
Abbreviations: COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; LVEF, left‐ventricular ejection fraction; hs‐cTnT: high‐sensitivity cardiac troponin T; PAD, peripheral artery disease.
Note: Model 1: Analyses were adjusted for all assessed variables, medications at admission (as listed in Table 1), hospital and admission year. Model 2: adjusted as model 1 with replacement of heart failure by left‐ventricular ejection fraction, categorized as ≥0.50, 0.40–0.49, 0.30–0.39 and < 0.30. Model 3: adjusted as model 1 with additional adjustment for high‐sensitivity cardiac troponin T (ln).