Fig. 2.

Analysis of baseline metabolites and cytokine production upon stimulation showing association and regulation of metabolites on immune response. a Heatmap of hierarchical clustering on correlation pattern between metabolites and cytokine production upon stimulation. b Cytokine variance explained by GM. The X-axis indicates explained variance represented by adjusted R squared. The Y-axis indicates stimulation types and measurement assays. Bar color shows different stimulations. c Violin and box plots of T cell–derived cytokine and monocyte-derived cytokine variance explained by GM. The X-axis indicates groups of cytokines grouped according to cell origins. The Y-axis indicates explained variance represented by adjusted R squared