TABLE 3.
Mortality of AP based on POF time of onset, duration, number, organ type, and sequence of organs affected
| Subgroups of POF | Mortality, n (%) | OR (95% CI) | p‐Value |
|---|---|---|---|
| By onset | |||
| Within 24 h | 17/74 (23.0) | Reference | 0.57 |
| Between Day 2–3 | 8/50 (16.0) | 0.64 (0.25–1.62) | |
| Between Day 4–7 | 5/29 (17.2) | 0.70 (0.23–2.11) | |
| After Day 7 | 4/13 (30.8) | 1.49 (0.41–5.45) | |
| By total duration | |||
| ≤7 days | 16/106 (15.1) | Reference | 0.11 |
| 8–14 days | 9/28 (32.1) | 2.66 (1.03–6.92) | |
| >14 days | 6/26 (23.1) | 1.69 (0.59–4.85) | |
| By number of failed organs | |||
| One organ (single POF) | 4/90 (4.4) | Reference | <0.001 |
| Two organ MOF | 15/45 (33.3) | 10.75 (3.31–34.94) | |
| Three organ MOF | 15/31 (48.4) | 20.16 (5.92–68.63) | |
| By organ type in single POF | |||
| Respiratory/CV | 4/73 (5.5) | Reference | 1 |
| Renal | 0/17 (0) | 0 (0–6.67) | |
| By organ type in two‐organ MOF | |||
| Renal with respiratory or CV | 11/40 (27.5) | Reference | 0.04 |
| Respiratory and CV | 4/5 (80.0) | 10.5 (1.1–105) | |
| By organ sequence in two‐organ MOF | |||
| Renal first | 4/27 (14.8) | Reference | 0.003 |
| Respiratory or CV first | 11/18 (61.1) | 9.0 (2.2–37.5) | |
| By organ sequence in three‐organ MOF | |||
| Renal first | 6/17 (35.3) | Reference | 0.16 |
| Respiratory or CV first | 9/14 (64.3) | 3.3 (0.75–14.5) | |
Abbreviations: AP, acute pancreatitis; CI, confidence interval; CV, cardiovascular; MOF, multiple organ failure; OR, odds ratio; POF, persistent organ failure.