Table 2.
BIS-11 and gray matter associations in general population (healthy adults)
| Study | n | Age | Impulsivity measure | Gray matter measure | Analysis | Relationship | Region |
|---|---|---|---|---|---|---|---|
| (Matsuo et al., 2009) | 62 (38 F) | 35.4 ± 12.1 | BIS-11 | Volume | Regression | Negative | R, L OFC (total; motor and non-planning subscales) |
| (Bjork et al., 2009) | 29 (11 F) | 37.4 ± 11.0 | BIS-11 | Volume | Regression | None | n/a |
| (Sala et al., 2011) | 15 (11 F) | 34.2 ± 8.1 | BIS-11 | Volume | Regression | None (only hippocampus and dlPFC assessed) | n/a |
| (Lee et al., 2011) | 18 (0 F) | 40.5 ± 7.5 | BIS-11 | Volume | Regression | Negative | L STG (attentional; motor) |
| Positive | L OFC, L Lateral Frontopolar Cortex (non-planning) | ||||||
| (Schilling et al., 2012) | 32 (18 F) | 35.2 ± 10.5 | BIS-11 (German version) | Cortical thickness | Regression | Negative | L MFG (total, attentional, motor and non-planning subscales) OFC; R MFG (total and motor subscale) |
| (Cho et al., 2013) | 34 (11 F) | 23.4 ± 4.3 | BIS-11 | Volume | Regression | Positive | L ACC; L DLPFC; R OFC; R, L medial PFC; R, L middle Cingulate (total; non-planning and attentional subscales) |
| (Deserno et al., 2015) | 24 (12 F) 26 (13 F) | 27.29 ± 3.7 27.58 ± 3.7 | BIS-11 | Density | Group (high-impulsive vs low-impulsive) | None | n/a |
| (Mei et al., 2015) | 41 (17 F) | 29.7 ± 10.1 | BIS-11 | Volume | Regression | None (only amygdala and hippocampus examined) | n/a |
| (Holmes et al., 2016) | 1015 (537 F) | 21.4 ± 3.1 | BIS-11 | Cortical Thickness | Regression | Negative | R, L MFG; R, L ACC (motor subscale) |
| 219 (133 F) | 21.2 ± 3.3 | BIS-11 | Cortical Thickness | Regression | Negative | R, L MFG; R, L ACC (motor subscale) | |
| (Ide et al., 2017) | 113 (66 F) | 32 ± 14 | BIS-11 | Volume | Regression | Positive | R, L parieto-occipital sulcus (total; attentional and non-planning subscales) |
| (Qiu et al., 2017) | 18 (0 F) | 24.0 ± 3.08 | BIS-11 | Cortical thickness and subcortical volume | Regression | None | n/a |
| (Korponay et al., 2017c) | 105 (65 F) | 48.6 ± 10.9 | BIS-11 | Volume | Regression | Negative | R Mofc (total; motor and non-planning) R, L paracingulate gyrus (non-planning subscale) |
| (Liu and Feng, 2017) | 85 (55 F) | 20.5 ± 2.07 | BIS-11 | Volume | Regression | Negative | L dlPFC, L calcarine gyrus (total) |
| Positive | R STG (total) | ||||||
| 84 (51 F) | 19.5 ± 1.4 | BIS-11 | Volume | Regression | Negative | L dlPFC, L MFG (total) | |
| (Tu et al., 2017) | 56 (34 F) | 33.9 ± 7.4 | BIS-11 (Chinese version) | Cortical Thickness | Regression | Negative | L Inferior, middle and medial PFC (total) |
| (Grodin et al., 2017) | 49 (26 F) | 38.8 ± 10.9 | BIS-11 | Volume Cortical thickness |
Regression Regression |
Negative Negative |
L ACC (total) R, L ACC (total) |
| (Kubera et al., 2018) | 54 (38 F) | 24.9 ± 4.02 | BIS-11 | Cortical thickness | Regression | Negative | L lingual gyrus; L superior temporal gyrus; R cuneus; R superior parietal gyrus (total) R, L pericalcarine gyrus (non-planning subscale) |
| (Ai et al., 2019) | 84 (43 F) | 21.3 ± 1.7 | BIS-11 (Chinese version) | Volume | Regression | Negative | R supplementary motor area; R paracentral lobule (total) |
| (Besteher et al., 2019) | 85 (57 F) | 24.1 ± 3.0 | BIS-11 (German version) | Volume | Regression | Positive | R inferior parietal gyrus; R postcentral gyrus; R supramarginal gyrus (total) |
| (Li et al., 2019) | 40 (2 F) | 24.4 ± 3.6 | BIS-11 | Sulcal depth, gyrificationand cortical thickness | Regression | None | n/a |
| (Rosenthal et al., 2019) | 62 (23 F) | 42.7 ± 11.69 | BIS-11 | Volume | Regression | None | n/a |
| (Zsido et al., 2019) | 29 (15 F) | 21.9 ± 2.1 | BIS-11 | Cortical thickness | Regression | Positive | R, L middle temporal cortex; L transverse temporal cortex; (total) |