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. 2021 Feb 11;9(1):91–101. doi: 10.1177/2050640620964619

TABLE 3.

Pharmacokinetic (PK) model simulations of attainment of PK targets of trough infliximab (IFX) concentrations of >3 mg/ml, >4 mg/ml, or >5 mg/ml for anti‐IFX antibody negative (ADA−) or positive (ADA+) patients in case of safety pausing IFX therapy in the entire third trimester of pregnancy (IFX‐stop); continuation of steady IFX maintenance therapy in the third trimester of pregnancy (IFX cont.); and nonpregnant patients receiving standard IFX maintenance therapy

Pregnant, IFX‐stop in third trimester Pregnant, IFX cont. in third trimester Nonpregnant patients
ADA− %n  > 3 μg/ml = 30 %n  > 4 μg/ml = 65 %n  > 4 μg/ml = 51
%n  > 4 μg/ml = 19 %n  > 5 μg/ml = 52 %n  > 5 μg/ml = 39
%n  > 5 μg/ml = 11 %n  > 3 μg/ml = 41 %n  > 3 μg/ml = 28
ADA+ %n  > 3 μg/ml = 3 %n  > 4 μg/ml = 17 %n  > 4 μg/ml = 11
%n  > 4 μg/ml = 1 %n  > 5 μg/ml = 9 %n  > 5 μg/ml = 5
%n  > 5 μg/ml = 1 %n  > 4 μg/ml = 3 %n  > 4 μg/ml = 2