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. 2021 Jul 5;13:108. doi: 10.1186/s13073-021-00924-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Transcriptional response to candidemia compared to other phenotypes. A* Differentially expressed genes (adj P <0.05) in response to different infection phenotypes. All genes, infection phenotypes compared to all others. B* Differentially expressed genes (adj P <0.05) in response to different infection phenotypes. All genes, Candida compared to each other phenotype. C Heatmap demonstrating differences in gene expression between infection phenotypes. D Genes involved in each phenotype of the multinomial classifier including model coefficients. Colors correspond to coefficient value (green: lower values, red: higher values). E Example of predicted probabilities of the specified condition over time. In this case, the subject’s predicted probability of candidemia decreased over time with antifungal treatment whereas the probability of a healthy state increased. *(https://bioinfogp.cnb.csic.es/tools/venny/index.html)