Table 3.
Published studies on kidney histopathology analysis in coronavirus disease 2019
| Histopathological Findings | Study | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Akilesh et al. (19) | Bradley et al. (15) | Bryce et al. (unpublished observations) | Golmai et al. (8) | Hanley et al. (24) | Kudose et al. (21) | Nasr et al. (20) | Remmelink et al. (14) | Santoriello et al. (11) | Sharma et al. (22) | Su et al. (9) | |
| Country | USA | USA | USA | USA | UK | USA | USA | Belgium | USA | USA | China |
| Sample | Biopsies | Autopsies | Autopsies | Biopsies | Autopsies | Biopsies | Biopsies | Autopsies | Autopsies | Biopsies | Autopsies |
| N | 17 | 14 | 25 | 12 | 9 | 17 | 13 | 17 | 42 | 10 | 26 |
| Age, yr | 54 (34–77) | 73 (67–77) | 69 (34–94) | 75 (57–77) | 73 (52–79) | 54 (22–72) | 52 | 72 (62–77) | 71 (38–97) | 66 (60–69) | 69 (39–87) |
| Hypertension, % | 82 | 71 | 63 | 75 | 40 | 65 | 85 | 59 | 73 | 70 | 55 |
| Diabetes, % | 29 | 36 | 40 | 33 | 20 | 18 | 46 | 53 | 42 | 30 | 15 |
| CKD, % | NA | 57 | 27 | 8 | 10 | NA | 44 | NA | 29 | 0 | 10 |
| AKI, % | 88 | 43 | NA | 100 | NA | 88 | 100 | 82 | 94 | 100 | 35 |
| FSGS, % | 65 | 7 | 0 | NA | 0 | 35 | 62 | NA | 3 | 10 | 8 |
| Diabetic nephropathy, % | 12 | 21 | 8 | 8 | 0 | NA | 23 | NA | 17 | 10 | 8 |
| Arteriosclerosis, % | NA | 79 | NA | 83 | 83 | 50 | 77 | NA | 85 | 80 | 69 |
| ATI, % | 82 | 79 | 24 | 100 | 100 | 71 | 100 | NA | 62 | 100 | 100 |
| GN, % | 18 | NA | 0 | 0 | 0 | 71 | 31 | NA | NA | 10 | 0 |
| TMA, % | 35 | NA | 0 | 0 | 17 | NA | 0 | 0 | 14 | 20 | 12 |
USA, United States; UK, United Kingdom; N, number; NA, not available; ATI, acute tubular injury; TMA, thrombotic microangiopathy.