Table 2.
Comparison of clinical and laboratory indices of patients with heat stroke and healthy controls according to the day of admission and outcome status.
| Characteristics | Healthy controls (n = 3) | Severe HS (n = 6) | P-value |
|---|---|---|---|
| Hemodynamic data | |||
| HR (beats/min) | 74.3 ± 7.74 | 96.85 ± 32.43 | <0.001 |
| MAP (mmHg) | 77.6 ± 6.99 | 72.15 ± 20.95 | 0.782 |
| Vasoactive drug, n (%) | 0 (0) | 3 (50) | <0.001 |
| Lactate (μmol/L) | 1.07 ± 0.47 | 3.11 ± 2.55 | <0.001 |
| Ventilatory data | |||
| PaO2/FiO2 | 378.7 ± 72.25 | 312.3 ± 67.56 | 0.007 |
| MV, n (%) | 0 (0) | 6 (67) | <0.001 |
| Inflammatory data | |||
| WBC (×109 cells/L) | 9.42 ± 3.14 | 10.81 ± 4.47 | <0.001 |
| PCT (ng/ml) | 0.34 ± 0.34 | 4.06 ± 4.14 | <0.001 |
| Hepatic data | |||
| ALT (U/L) | 25.51 ± 13.7 | 1,448 ± 2,360 | <0.001 |
| AST (U/L) | 22.4 ± 13.8 | 2,144 ± 3,861 | 0.001 |
| TBil (µmol/L) | 9.23 ± 4.45 | 62.83 ± 93.67 | <0.001 |
| ALB (g/L) | 40.79 ± 5.36 | 37.56 ± 3.51 | 0.302 |
| Renal data | |||
| Cr (μmol/L) | 95.4 ± 27.28 | 161.1 ± 84.24 | <0.001 |
| BUN (mmol/L) | 5.51 ± 2.19 | 8.03 ± 6.73 | <0.001 |
| Urine output (ml/d) | 2,680 ± 727.2 | 2,095 ± 1,369 | <0.001 |
| Coagulation data | |||
| PT (s) | 13.39 ± 0.93 | 25.67 ± 15.61 | <0.001 |
| INR | 13.39 ± 0.93 | 2.50 ± 2.21 | <0.001 |
| Fib (g/L) | 3.53 ± 0.66 | 2.05 ± 0.76 | < 0.001 |
| PLT (×109/L) | 219.6 ± 65.05 | 101.2 ± 61.35 | < 0.001 |
| D-dimer | 1.46 ± 1.32 | 15.77 ± 5.96 | < 0.001 |
| FDP | 6.83 ± 2.88 | 100.8 ± 184.3 | 0.001 |
| Rhabdomyo data | |||
| CK (μg/L) | 54.33 ± 23.52 | 5,155 ± 5,888 | <0.001 |
| MYO (μg/L) | 48.15 ± 24.91 | 1,374 ± 964.4 | <0.001 |
| Cardiac data | |||
| CK-MB | 2.54 ± 1.45 | 39.83 ± 50.51 | <0.001 |
| cTnI | 12.76 ± 9.94 | 874.2 ± 1134 | 0.02 |
| CNS data | |||
| GCS score | 15 ± 0 | 8.3 ± 4.28 | <0.001 |
ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CK, creatine kinase; CK-MB, CK-myocardial band; CNS, central nervous system; Cr, creatinine; cTnI, cardiac troponin I; FDP, fibrin degradation product; Fib, fibrin; FiO2, percentage of inspired oxygen; GCS, Glasgow Coma Scale; HR, heart rate; INR, international normalized ratio; MAP, mean arterial pressure; MV, mechanical ventilation; MYO, myoglobin; PaO2, partial pressure of arterial oxygen; PCT, procalcitonin; PLT, platelet; PT, prothrombin time; TBil, total bilirubin; WBC, white blood cell.