Table 2.
Premature permanent discontinuation of anticoagulation
| Parameter | VKA (n=44) | Rivaroxaban (n=46) | Rivaroxaban and Vitamin K2 (n=42) a | P b |
|---|---|---|---|---|
| Any withdrawal, n (%) | 14 (31.8) | 9 (19.6) | 10 (23.8) | 0.42 |
| Time on anticoagulation/total observation time | 0.89 | 0.88 | 0.87 | 0.71 |
| Bleeding, n | 8 | 8 | 9 | |
| Calciphylaxis, n | 2 | 0 | 0 | |
| Labile INR, n | 3 | — | — | |
| Clinical deterioration, n | 1 | 0 | 0 | |
| Registration on transplant list, n | 0 | 1 | 0 | |
| Wish of the patient, n | 0 | 0 | 1 |
a
Only rivaroxaban was withdrawn and vitamin K2 supplements were continued.
b
According to Fisher exact or Kruskal–Wallis test.