Melatonin profiles for a treatment participant and a control participant. Left panel: Melatonin profile for each constant posture (CP) (baseline, night shift, evening shift, and day shift) of a male treatment participant. Right panel: Melatonin profile for each CP of a female control participant. Black bars represent the scheduled sleep times, diagonal bars represent the work hours and the dashed vertical line represents midnight. During the night shift CP, the control participant showed no overlap in melatonin and sleep timing, whereas the treatment participant did.