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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Am J Med Genet A. 2020 Sep 4;182(11):2581–2593. doi: 10.1002/ajmg.a.61830

TABLE 3.

Co-occurring defects among cases with non-syndromic omphalocele (N = 404) ordered by frequency, Texas Birth Defects Registry, 1999–2014

Defecta No. of cases Percent co-occurrence with non-syndromic omphalocele
Ostium secundum type atrial septal defect 120 29.7
Ventricular septal defect 73 18.1
Obstructive defects of renal pelvis and ureter 40 9.9
Atresia and stenosis of large intestine rectum and anal canal 30 7.4
Other deformities of feet (e.g., clubfoot, NOSb) 26 6.4
Other specified anomalies of the heart (e.g., ventricular septal thickening) 24 5.9
Anomalies of spine 23 5.7
Anomalies of diaphragm 22 5.4
Other anomalies of aorta (e.g., narrowing of aorta) 22 5.4
Spina bifida 20 5.0
Other anomalies of ribs and sternum (e.g., less than 12 rib pairs) 17 4.2
Atresia and stenosis of small intestine 17 4.2
Other anomalies of intestine (e.g., short colon) 17 4.2
Renal agenesis and dysgenesis 16 4.0
Disorder of sexual development 15 3.7
Anomalies of intestinal fixation 15 3.7
Tetralogy of Fallot 15 3.7
Anomalies of great veins 15 3.7
Other unspecified anomalies of face and neck (e.g., microstomia) 14 3.5
Microcephalus 14 3.5
Anomalies of pulmonary artery 13 3.2
Persistent omphalomesenteric duct 12 3.0
Anomalies of gallbladder bile ducts and liver 12 3.0
Cleft lip with or without cleft palate 12 3.0
Anencephalus 11 2.7
a

Full range of BPA codes is listed in Table S2.

b

NOS, not otherwise specified.