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. Author manuscript; available in PMC: 2021 Jul 6.
Published in final edited form as: Radiat Res. 2021 Jun 1;195(6):522–540. doi: 10.1667/RADE-20-00237.1

FIG. 1.

FIG. 1.

Panel A: Experimental timeline for addition of low-to-moderate-dose whole-brain radiation treatment (WBRT) to in situ vaccination (ISV) + anti-CTLA-4 (a-CTLA-4) regimen. The ISV approach includes radiation and IT-IC. Panel B: Survival curve for mice receiving WBRT in addition to ISV + anti-CTLA-4 regimen, and treatment controls (**P < 0.01, ***P < 0.001, Kaplan-Meier, n ≥ 10, at least two independent animal experiments).