Figure 2.

Schematic illustrating the observed spectrum of clinical courses and diagnostic outcomes following molecular diagnosis of KCNMA1-linked channelopathy. If there is more than one clinical phenotype for episodic or paroxysmal symptoms, each symptom or episode should be evaluated independently on EEG, given the co-occurrence of epilepsy and other non-epileptic paroxysms. Long-term EEG is often helpful. PNKD3 denotes PNKD associated with a confirmed KCNMA1 mutation. GTC-Generalized Tonic-Clonic, EEG-electroencephalogram, PNKD- paroxysmal nonkinesigenic dyskinesia, PED- paroxysmal exertion-induced dyskinesia, PKD- paroxysmal kinesigenic dyskinesia