FIGURE 3.

Effects of STAT3 gene overexpression on cell proliferation and endogenous FST expression. (A,B) Effect of STAT3 overexpression on the proliferation of SFFs and HaCaT cells. (C,D) Expression levels of Ki67 and PCNA in the SFFs transfected with pCMV-Myc STAT3. (E,F) Effects of STAT3 overexpression on the endogenous expression of FST gene in SFFs and HaCaT cells. Fold change was calculated referring to the expression of the SFFs transfected with pCMV-Myc at 48 h. All data are representative of three independent experiments and display as the mean ± SEM. For each figure layer, statistical significance was indicated by *P < 0.05, **P < 0.01, and different letters above error bars indicated a statistical significance (P < 0.05).