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. 2021 Jul 5;26(1):111–116. doi: 10.1080/13510002.2021.1948774

Figure 1.

Figure 1.

Signaling pathways associated with Sestrin2.

Note: ER, endoplasmic reticulum; HIF-1α, hypoxia inducible factor-1α; Nrf2, nuclear factor-E2 -related factor 2; AMPK, adenosine monophosphate-activated protein kinase; mTOR, mammalian target of rapamycin; MAPK8/JNK1, mitogen-activated protein kinases 8/c-Jun N-terminal kinase 1; Keap1, kelch-like ECH-related protein 1.