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. 2021 Jul 3;59(1):882–890. doi: 10.1080/13880209.2021.1944221

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — LC-MS/MS chromatograms oflaurolitsine and IS nuciferine in different matrix. (A) Blank biological matrix; (B) LLOQ sample of different biological matrix (laurolistine 1 ng/mL⁻¹); (C) rat plasma of 1 h after i.v. administration laurolistine, rat urine of 0–4 h after p.o. administration laurolistine, rat liver tissue of 2 h after p.o. administration laurolistine; (D) rat plasma of 1 h after p.o. administration laurolitsine.