Table 5.

Pharmacokinetic parameters of laurolitsine after i.g. and i.v. admininstration.

PK parameters	i.v. Admininstration (2 mg/kg)	i.g. Admininstration (10 mg/kg)
t1/2 (h)	1.67 ± 1.83	3.73 ± 2.48
Cmax (ng/mL)	100.05 ± 17.00	14.11 ± 3.30
Tmax(h)	0.083	0.47 ± 0.18
AUC0-t (h·ng/mL)	49.98 ± 7.39	40.62 ± 9.57
AUC0-∞ (h·ng/mL)	52.29 ± 7.98	47.77 ± 10.44
MRT (0-t)(h)	0.61 ± 0.22	2.90 ± 0.53
Vz(L/kg)	86.04 ± 86.75	1207.59 ± 799.48
CLz (L/h/kg)	38.96 ± 5.86	218.26 ± 51.89
F(%)	–	18.17