Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 2;16:4481–4494. doi: 10.2147/IJN.S316564

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Radwan et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Electron micrographs of retinal sections from negative control show normal organized photoreceptor cell layer (PRL), the photoreceptor cells are with regular horizontal lamellar discs (D). Outer nuclear cell layer (ONL) shows minimal intercellular spaces between nuclei (N) of photoreceptor cells. Normal blood vessel (BV) with normal thickness of the basement membrane is noticed. Electron micrographs from positive control show disorganized photoreceptor cell layer (PRL) with increased interdisc spaces (*), photoreceptor cells show distorted lamellar discs (D) and vacuolated outer segments (OS). ONL shows wide spaces between photoreceptor cells’ nuclei (N). Notice BV with thickened basement membrane. Electron micrographs from Apa-BSA-NPs (IVT) group show PRL with few distorted lamellar discs and vacuolated OS and increased interdisc spaces (*), these findings are more prominent in Apa-BSA-NPs (Topical) group. Electron micrographs from Apa-HA-BSA-NPs (IVT) and Apa-HA-BSA-NPs (Topical) groups show almost normal retinal ultra-structure. All treated groups showed normal BV basement membrane thickness.