Table 2.
Pathway Analysis Results Produced Using MetaboAnalyst 5.0
| Pathway Name | Raw p | Impact |
|---|---|---|
| Serum | ||
| Alanine, aspartate, and glutamate metabolism | 9.50e-04 | 0.22 |
| Colon | ||
| Aminoacyl-trna biosynthesis | 8.85E-11 | 0.17 |
| Glycine, serine, and threonine metabolism | 1.53e-03 | 0.50 |
| Glyoxylate and dicarboxylate metabolism | 2.13e-02 | 0.15 |
| Glutathione metabolism | 1.65e-02 | 0.10 |
| Heart | ||
| Arginine biosynthesis | 5.01E-03 | 0.12 |
| Alanine, aspartate, and glutamate metabolism | 1.95E-02 | 0.20 |
| Phenylalanine, tyrosine, and tryptophan biosynthesis | 3.15E-02 | 0.50 |
| D-glutamine and D-glutamate metabolism | 4.69E-02 | 0.50 |
| Arginine and proline metabolism | 3.48E-02 | 0.16 |
| Cortex | ||
| Alanine, aspartate, and glutamate metabolism | 6.06E-05 | 0.42 |
| Arginine biosynthesis | 1.72E-04 | 0.12 |
| Arginine and proline metabolism | 4.04E-02 | 0.16 |
| Purine metabolism | 1.67E-02 | 0.02 |
| Glutathione metabolism | 2.28E-02 | 0.02 |
| Glyoxylate and dicarboxylate metabolism | 2.94E-02 | 0.03 |
| Phenylalanine, tyrosine, and tryptophan biosynthesis | 3.41E-02 | 0.50 |
| Hippocampus | ||
| Alanine, aspartate, and glutamate metabolism | 6.06E-05 | 0.42 |
| Arginine biosynthesis | 1.72E-04 | 0.12 |
| Glyoxylate and dicarboxylate metabolism | 2.15e-03 | 0.03 |
| Purine metabolism | 1.67e-02 | 0.02 |
| Glutathione metabolism | 2.28e-02 | 0.03 |
| Phenylalanine, tyrosine, and tryptophan biosynthesis | 3.41e-02 | 0.50 |
| Brown fat | ||
| Aminoacyl-trna biosynthesis | 3.09E-07 | 0.17 |
| Cysteine and methionine metabolism | 2.26E-02 | 0.13 |
| Alanine, aspartate, and glutamate metabolism | 1.65E-02 | 0.22 |