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An algorithmic flowchart of in vivo validation of our current predictions by means of publicly available RNA-Seq data on differentially expressed genes (DEGs) of domestic vs. wild animals. RA, rheumatoid arthritis; effect on RA, contributes to (↑), relieves (↓); NCA, nearest common ancestor; PADJ, significance [Fisher’s Z-test with those corrections on multiple comparisons that have been published by Albert et al. (2012), Hekman et al. (2018), and Yang et al. (2018)].
