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. 2021 Jul 6;17(7):e1009689. doi: 10.1371/journal.ppat.1009689

Table 2. Developed VZV BAC and degron containing VZV recombinants.

Gene Protein Function Terminus attached Resulting VZV
ORF4 IE4 regulator of mRNA export N replication conditional
ORF6 ORF6p DNA primase C not viable
ORF9 ORF9p tegument protein C replication conditional
ORF10 ORF10p transcriptional activator N or C not replication conditional
ORF29 ORF29p ssDNA binding protein N or C not viable
ORF52 ORF52p DNA helicase C not viable
ORF55 ORF55p DNA helicase C not replication conditional
ORF61 ORF61p transcriptional regulator N or C not viable
ORF62 IE62 major transcriptional activator N or C not replication conditional
ORF63 IE63 transcriptional regulator C replication conditional