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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Ann Neurol. 2021 Feb 24;89(5):952–966. doi: 10.1002/ana.26043

Figure 7. Anti-ApoE ASO treatment reduces NfL levels in plasma of 9-month-old P301S/ApoE4 mice.

Figure 7.

(A) Neurofilament Light Chain (NfL) levels in plasma of 9-month-old cASO and anti-ApoE ASO-treated mice. N=12/group. Student`s t-test. *p<0.05. (B-D) Correlation between NfL levels in plasma and hippocampal volume (B) (R2=0.1831, p=0.0598); cortical volume (C) (R2=0.07101, p=0.2561) and ventricular volume (C) (R2=0.2063, p=0.0443). N=24 independent animals. Pearson`s correlation test. All data represented as mean ± SEM.