TABLE 1.
Clinical and Radiographic Characteristics of Patients With Chemotherapy-associated PRES
Age (N = 70) | 18–79, median: 55 |
Sex (%) | |
Female | 77 |
Male | 23 |
Blood pressure (N = 63)* | 106–240/95–124, median: 170/92.5 |
Days until onset (N = 63)† | 1–60, median: 8 |
Duration(N = 36)‡ | 1–14, median: 4 |
Fatal (%) | 7 |
Symptoms (%) | |
Seizure | 64 |
Altered mental status | 47 |
Visual changes | 43 |
Headache | 40 |
Other neurological deficit | 19 |
Coma | 14 |
MRI findings (%) | |
Occipital | 93 |
Parietal | 57 |
Frontal | 26 |
Temporal | 17 |
Only case reports that included numeric measurements of presenting blood pressures were included.
Number of days between last administration of implicated chemotherapy and onset of posterior reversible encephalopathy syndrome symptoms.
Duration of symptoms was defined as number of days to significant clinical improvement.
MRI indicates magnetic resonance imaging.