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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Curr Protoc Microbiol. 2020 Dec;59(1):e118. doi: 10.1002/cpmc.118

Figure 1.

Figure 1.

Tick proteins from salivary glands and midguts provide ideal targets for countermeasure development. By using LC-MS/MS proteomics, proteins can be profiled from salivary glands, many of which can be secreted during blood feeding and found within the feeding site and the formed cement cone. Midgut proteins, especially exposed proteins in the lumen, provide critical areas for pathogen interactions and may aid in pathogen dissemination through the midgut epithelial layer to systemically infect the tick.