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. 2021 Jul 1;28(7):1262–1274.e5. doi: 10.1016/j.stem.2021.02.005

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Ancestral clones marking adult tissue homeostasis are spatially confined

The distribution of six clones dated to adult tissue maintenance of the left glandular subunit is displayed. The location of individual ancestral clones is highlighted with an arrow. All adult clones can be found in the corresponding embryonic territory. The embryonic clone represented by cluster 76 simultaneously marks the most recent common ancestor of the six adult clones displayed. Microdissections with positive contribution from the clone are circled in black, whereas those with zero contribution are circled in gray. See also Figure S6.