Figure 5.
Expression of mCherry-hPMCA2w/b in peripheral organs of bigenic mice with the multiple dose tamoxifen protocol. A, Hematoxylin and eosin staining showing that the gross histology of the brain from bigenic (CalExflox/wt; Aldh1l1-Cre/ERT2) mice was not altered. B, C, IHC images showing mCherry-hMPCA2w/b expression from seven peripheral organs including the heart, lungs, liver, spleen, small intestine, kidney, and muscle from the control (B) and bigenic (C) mice. mCherry-CalEx expression was detected in the small intestine but not in other organs.