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RYGB surgery restores glucose-stimulated insulin secretion in pancreatic islets. Cell medium insulin concentration after incubation of isolated islets in either 2 mM or 20 mM glucose solutions. Lean n = 4 rats, Sham n = 7 rats, RYGB n = 7 rats, pair-fed n = 9 rats. Data are shown as the means ± SE Data were assessed by one-way ANOVA with Tukey’s multiple comparisons. *P < 0.05, **P < 0.01. RYGB, Roux-en-Y gastric bypass.
