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. 2021 Feb 12;320(4):H1526–H1534. doi: 10.1152/ajpheart.00883.2020

Figure 4.

Figure 4.

Losartan treatment ameliorates chronic, inhaled nicotine-induced right ventricular (RV) remodeling assessed by echocardiography. RV free wall thickness in diastole (RV FWT;d) (A) and RV internal diameter in diastole (RVID;d) (B) in air- and nicotine-exposed mice with or without losartan treatment. Heart rate was maintained between 400 and 550 beats/min. Data are displayed as means ± SE. n = 7–12/group; *P < 0.05, ****P < 0.0001 (two-way ANOVA with Tukey–Kramer post hoc test).