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. 2021 Apr 22;121(8):2207–2217. doi: 10.1007/s00421-021-04693-6

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© The Author(s) 2021

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Fig. 1 — Study protocol. All lower body negative pressure (LBNP) levels lasted for 6 min, with 2 min of stabilization, 2 min of rest and 2 min of isometric hand grip (IHG). Subjects were randomized to start with IHG or rest at LBNP 0, and the order of rest/IHG on the following LBNP levels was alternated