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. 2021 Jul 7;109:192–194. doi: 10.1016/j.ijid.2021.07.007

Table 2.

Association analysis between bad outcome and drug exposure (adjusted by PS)*,⁎⁎

Mortality at day 15 Mortality at day 30 Overall mortality
Drug family OR 95% CI p OR 95%CI p OR 95%CI p
ACE2 inhibitor 0.78 (0.5-1.2) 0.2 0.73 (0.5-1.0) 0.07 0.74 (0.5-1.0) 0.08
Inhaled corticoids 0.61 (0.3-1.1) 0.1 0.52 (0.3-0.9) 0.03 0.58 (0.3-1.00) 0.05
Statins 0.77 (0.5-1.2) 0.2 0.65 (0.4-0.9) 0.03 0.69 (0.5-1.0) 0.06
Vitamin D derivatives 0.87 (0.6-1.3) 0.5 0.8 (0.6-1.2) 0.2 0.79 (0.6-1.1) 0.2
Platelet antiaggregants 1.14 (0.8-1.6) 0.4 1.09 (0.8-1.5) 0.6 1.09 (0.8-1.5) 0.6
Anticoagulants 0.91 (0.6-1.4) 0.7 0.78 (0.5-1.2) 0.5 0.76 (0.5-1.1) 0.2
Oral corticoids 1.27 (0.7-2.2) 0.4 1.57 (0.9-2.6) 0.08 1.68 (1.0-2.8) 0.04
ARA-II blockers 1.23 (0.7-1.7) 0.6 1.09 (0.7-1.6) 0.7 1.01 (0.7-1.5) 0.9

PS included age, gender, respiratory, cardiovascular or cerebrovascular comorbidities, hypertension, dementia, diabetes mellitus type II, Barthel score, frailty score, size of the LTC facility in number of residents.

⁎⁎

Adjustments included drugs under study