Table 2.

Univariate meta-regression analysis between effect size and possible contributors to heterogeneity.

	Number of studies	t	p-value	Explained heterogeneity
Age	54	0.43	0.67	0%
Gender	54	−0.54	0.59	0%
Time of recruitment commencement	54	1.44	0.15	3%
White blood cell count	44	3.51	0.001	22%
C-reactive protein	46	1.17	0.25	1%
Procalcitonin	23	1.75	0.10	9%
Aspartate aminotransferase	47	2.81	0.007	15%
Alanine aminotransferase	48	−0.73	0.47	0%
Albumin	37	−1.53	0.13	4%
D-dimer	40	2.47	0.02	13%
Troponin	26	3.83	0.001	39%
Myoglobin	17	2.91	0.01	36%
Brain natriuretic peptide	19	2.67	0.02	29%
Creatinine	43	1.17	0.25	5%
Lactate dehydrogenase	34	2.40	0.02	15%
Diabetes	37	0.56	0.58	0%
Cardiovascular disease	34	−0.80	0.43	0%
Hypertension	39	0.59	0.56	0%