Table 1.
Map of post-exercise effects on cancer cell viability / growth
| Study | Participants | Cancer cell line | Exercise bout | Post-exercise time point | ||||
|---|---|---|---|---|---|---|---|---|
| 0 | 1-h | 2-h | 4-h | 24-h | ||||
| Baldelli et al. (2020) | Young and healthy males and females (n = 30) | LNCaP (prostate) and MDA-MB-231 (breast) | Cycling. Progressive aerobic (4 × 5-min at 50%, 55%, 60%, 70% Wmax) and HIIE (10 × 90-s at 90% Wmax interspersed with 180-s at 55% Wmax) followed by exercise to exhaustion at 90% Wmax | ↓ | ↓ | ↓ | ||
| Dethlefsen et al. (2016) | Middle-aged women with breast cancer (n = 20) | MCF-7 and MDA-MB-231 (breast) | 30 min warm up followed by 60 min of whole-body resistance exercise and 30 min of HIIE cycling (80–85% HRmax). No other details provided | ↓ | ||||
| Dethlefsen et al. (2017a ) | Young healthy females (n = 7) | MCF-7 and MDA-MB-231 (breast) | Moderate intensity continuous cycling (2-h at 55% VO2max) | ↓ | ||||
| Devin et al. (2019) | Male colon cancer survivors (n = 10) | CaCO-2 and LoVo (colon) | HIIE cycling (4 × 4 min at 85–95% HRmax) | ↓ | ↔ | |||
| Hwang et al. (2020) | Healthy young males (n = 12) | PC3 and LNCaP (prostate) | Moderate intensity continuous cycling (20-min at 50% VO2max followed by 45-min at 65% VO2max) | ↓ | ||||
| Healthy older males (n = 12) | PC3 and LNCaP (prostate) | Moderate intensity continuous cycling (20-min at 50% VO2max followed by 45-min at 65% VO2max) | ↔ | |||||
| Kurgan et al. (2017) | Healthy young males (n = 6) | A549 (lung) | HIIE cycling (6 × 1-min at 90% Wmax) | ↓ | ↓ | ↓ | ||
| Rundqvist et al. (2013) | Young healthy males (n = 10) | LNCaP (colon) | Moderate intensity continuous cycling (20-min at 50% VO2max followed by 40-min at 65% VO2max) | ↓ | ||||
Wmax maximal power output achieved during an incremental exercise test to volitional exhaustion, HIIE High-intensity interval exercise, HRmax maximal heart rate
↓Decreased cancer cell viability/growth; ↔ , no change in cancer cell viability /growth