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. 2021 Jul 6;17(7):66. doi: 10.1007/s11306-021-01815-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A 2D PCA score plot displaying the fecal metabolomics data from dogs before (T0, red) and after (T1, blue) weight reduction by feeding a therapeutic diet. B 2D PCA score plot displaying the data from the 13 metabolites which were significantly different in their peak intensity before (T0, red) and after (T1, blue) weight loss reduction. Ellipses represent the 95% confidence interval of the metabolite profile for each group