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. 2021 Jun 23;8:686644. doi: 10.3389/fvets.2021.686644

Table 2.

Clinical signs associated with canine granulocytic anaplasmosis after natural infection and corresponding frequency recorded in several studies.

Clinical sign Frequency (%) Number of dogs included in the study References
Fever 84
47
61
46
89
52
100
57
67
60
67
32
49
18
26
18
60
8
28
6
15
61
(26)
(31)
(25)
(33)
(27)
(45)
(24)
(13)
(312)
(60)
(35)
Fever, lethargy 88 17 (29)
Fever, lethargy, depression 93 14 (30)
Fever, lethargy, anorexia 51 107 (34)
Lethargy/depression 94
88
74
72
67
81
67
26
50
83
73
18
17
34
18
49
26
60
28
6
63
15
(25)
(29)
(26)
(27)
(31)
(33)
(45)
(13)
(312)
(35)
(60)
Inappetence/anorexia 62
33
58
55
29
87
88
50
63
67
34
49
26
60
51
8
17
6
63
15
(26)
(31)
(33)
(45)
(13)
(24)
(29)
(312)
(35)
(60)
Weight loss 25 8 (24)
Pale mucous membrane 28
12
50
18
8
6
(25)
(24)
(312)
Dehydratation 37 8 (24)
Musculoskeletal Signs
Lameness 32
16
11
50
23
34
16
16
27
34
49
18
26
60
107
28
63
15
(26)
(31)
(25)
(33)
(45)
(34)
(13)
(35)
(60)
Joint swelling 62
6
19
55
14
33
8
34
26
18
28
6
(24)
(26)
(33)
(27)
(13)
(312)
Digestive signs 23
13
107
15
(34)
(60)
Vomiting 24
11
15
6
50
8
34
18
26
18
6
63
(26)
(25)
(33)
(27)
(312)
(35)
Diarrhea 9
17
50
14
34
18
6
63
(26)
(25)
(312)
(35)
Abdominal pain 9 34 (26)
Tense abdomen 28
40
18
63
(25)
(35)
Lymphadenopathy 32
19
6
13
6
34
26
18
17
63
(26)
(33)
(27)
(29)
(35)
Splenomegaly 12
40
13
100
17
84
34
60
17
18
6
57
(26)
(45)
(29)
(25)
(312)
(35)
Hepathomegaly 8
33
26
6
(33)
(312)
Hepatosplenomegaly 7
12
17
57
(29)
(35)
RESPIRATORY SIGNS
High respiratory rate 29
2
34
63
(26)
(35)
Cough 8
37
3
26
8
63
(33)
(24)
(35)
Respiratory or urinary tract disease 7 91 (34)
Bleeding disorders 12
13
66
63
(34)
(35)
Petechiae 11
3
18
63
(25)
(35)
Epistaxis 6
8
6
4
2
18
26
18
28
63
(25)
(33)
(27)
(13)
(35)
Melena 6
17
18
6
(25)
(312)
Gingival bleeding, hematoma, fresh blood in feces, pulmonary and vaginal hemorrage 2 63 (35)
Neurological signs 7 28 (13)
Left cerebral dysfunction 6 18 (27)
Cervical pain 6
2
18
63
(27)
(35)
Proprioceptifon deficit 7 17 (29)
Seizures 15
7
2
40
17
63
(34)
(29)
(35)
Ataxia 67
7
6
15
(312)
(60)
Skin disease 10
12
61
33
(34)
(313)