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. 2021 Jun 23;8:686644. doi: 10.3389/fvets.2021.686644

Table 4.

Serum biochemistry abormalities associated with canine granulocytic anaplasmosis after natural infection and corresponding frequencies recorded in several studies.

Serum biochemistry abnormalities Frequency (%) Number of dogs References
Hyperproteinemia 12
43
49
62
(31)
(35)
Hypoproteinemia 10
20
2
49
11
62
(31)
(29)
(35)
Hypoalbuminemia 44
29
17
28
44
55
50
62
27
49
23
60
9
18
6
61
(26)
(31)
(33)
(45)
(29)
(25)
(312)
(35)
Hyperglobulinemia 50
38
6
61
(312)
(35)
Serum protein electrophoresis A/G ratio <0.8 21 145 (28)
CIC 80 204 (28)
Hypophosphatemia 62 8 (24)
Increased ALP 52
59
26
43
75
100
7
67
27
49
23
60
8
9
14
61
(26)
(31)
(33)
(45)
(24)
(29)
(30)
(35)
Increased ALT 30
35
18
27
49
62
(26)
(31)
(35)
Increased bilirubin 37
31
34
27
49
61
(26)
(31)
(35)
Azotemia 27
3
49
62
(31)
(35)
Increased aPTT 60
55
10
29
(25)
(35)
Increased PT 30
34
10
29
(25)
(35)

A/G ratio, albumin to globulins ratio; ALP, alkaline phosphatase; ALT, alanine aminotransferase; apt, activated partial thromboplastin time; CIC, circulating immune complexes.