Fig. 4.

TRIM31 deficiency maintained mitochondria homeostasis in brain of mice subjected to middle cerebral artery occlusion (MCAO). (A) TRIM31 deficiency improved ultrastructural defects of neuronal mitochondria from mice subjected to MCAO. (B–D) The effect of TRIM31 on the expression of protein related to mitochondrial dynamics, PGC-1α, MFN1, MEN2 and DRP1, in the mice brain after 24 h of MCAO. Scale bars: 10 μm. Data were presented as the mean ± SEM of 3 independent experiments. *p < 0.05 vs. indicated group.