Table 1.
Patient demographic and clinical and laboratory data for the discovery cohort.
| Parameter | NAFL | NASH |
|---|---|---|
| Number | 26 | 12 |
| Age (years) | 38.38 ± 1.99 | 44.83 ± 2.68 |
| Gender (M/F) | 10/16 | 4/8 |
| BMI (kg/m2) | 44.68 ± 1.32 | 41.56 ± 1.27 |
| Hematology and biochemistry | ||
| AST (U/L) | 27.19 ± 2.55 | 30.92 ± 3.16 |
| ALT (U/L) | 39.62 ± 6.96 | 45.08 ± 5.38 |
| GGT (U/L) | 29.36 ± 4.22 | 37.58 ± 3.42 |
| Glucose (mg/dl) | 93.58 ± 2.13 | 100.58 ± 3.68 |
| Triglycerides (mg/ml) | 118.44 ± 5.82 | 155.91 ± 20.63 |
| Total cholesterol (mg/ml) | 191.27 ± 7.41 | 197.67 ± 10.83 |
| HDL-cholesterol (mg/ml) | 46.27 ± 2.69 | 44.08 ± 2.57 |
| LDL-cholesterol (mmol/dl) | 125.00 ± 7.61 | 125.73 ± 10.11 |
| Total bilirubin (mg/dl) | 0.69 ± 0.08 | 0.74 ± 0.08 |
| Platelets (109/L) | 280.42 ± 17.32 | 300.82 ± 11.70 |
| INR | 0.97± 0.01 | 0.94 ± 0.02 |
Data are expressed as mean ± SEM. Information not available for non-obese controls.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; F, female; GGT, γ-glutamyl transferase; HDL, high-density lipoprotein; INR, international normalized ratio; LDL, low-density lipoprotein; M, male; NAFL, nonalcoholic fatty liver; NASH, nonalcoholic steatohepatitis.