Fig. 1.

Study workflow

(a) Radiomic workflow. Multi-sequence MRI images were used for breast tumor and ALN region identification and the delineation of regions of interest, then features were extracted using 3D Slicer software for the signatures construction. (b) The association between MRI radiomics and tumor microenvironment. MRI=magnetic resonance imaging. ALN = axillary lymph node. T1+C=contrast-enhanced T1-weighted imaging. T2WI=T2-weighted imaging. DWI-ADC=diffusion-weighted imaging quantitatively measured the apparent diffusion coefficient. SVM=support vector machine. DC= dendritic cell. MDSC=myeloid-derived suppressor cell. NK=natural killer cell. LncRNA=long non-coding RNA.