Table 2.
The differentiation of radiomics before and after neoadjuvant therapy.
| Radiomic features class | Tumor region |
ALN region |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T1+C |
T2WI |
DWI-ADC |
T1+C |
T2WI |
DWI-ADC |
||||||||
| Up-regulation features | Down-regulation features | Up-regulation features | Down-regulation features | Up-regulation features | Down-regulation features | Up-regulation features | Down-regulation features | Up-regulation features | Down-regulation features | Up-regulation features | Down-regulation features | ||
| Shape | 1 | 2 | 1 | 1 | 2 | 0 | 0 | 2 | 0 | 2 | 4 | 0 | |
| First-order | 0 | 0 | 1 | 2 | 2 | 1 | 3 | 3 | 0 | 1 | 1 | 0 | |
| GLCM | 1 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |
| GLSZM | 2 | 1 | 2 | 4 | 7 | 2 | 3 | 0 | 0 | 0 | 2 | 0 | |
| GLDM | 5 | 2 | 3 | 2 | 6 | 1 | 4 | 5 | 2 | 6 | 3 | 2 | |
| GLRLM | 1 | 2 | 2 | 2 | 3 | 3 | 2 | 4 | 3 | 8 | 3 | 3 | |
| NGTDM | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Number of key radiomic features under each class that differentiated (P < 0·05) before and after neoadjuvant therapy in 45 patients from the prospective-retrospective validation cohort. ALN=axillary lymph node. T1+C=contrast-enhanced T1-weighted imaging. T2WI=T2-weighted imaging. DWI-ADC=diffusion-weighted imaging quantitatively measured the apparent diffusion coefficient. GLCM=gray-level co-occurrence matrix. GLSZM=gray-level size zone matrix. GLDM=gray-level dependence matrix. GLRLM=gray-level run length matrix. NGTDM=neighboring gray-tone difference matrix.