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. 2021 Jul 4;69:103464. doi: 10.1016/j.ebiom.2021.103464

Fig. 1.

Fig. 1

Characterization of lymphocyte subsets and T cell phenotype profiles in cHBV patients with HBsAg loss. Radar plots depicting the fold changes of the median numbers of lymphocyte subsets (a), median percentages of CD4+T cells (b) and CD8+T cells (c) expressing different T cell markers in the PBMC for HBsAg retained patients (sAg-R, n = 141) and HBsAg loss patients (sAg-L, n = 31) compared to those of healthy controls (HC, n = 24). The median values of all detection indexes of HC are defined as 1. Representative flow cytometry analyses showing HLA-DR, CD25 expression on CD4+T cells (b) and HLA-DR expression on CD8+T cells (c) obtained from HC, sAg-R and sAg-L patients. Data are presented as median and statistical analysis was performed by GraphPad Prism using Kruskal-Wallis test followed by Dunn's multiple comparisons test; *P < 0·05; **P < 0·01; ***P < 0·001; ****P < 0·0001. Abbreviation: ns, not significant.