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Caspase-11 was upregulated and activated in liver during MCD-induced hepatic steatosis. Wild-type (WT) mice were treated with MCD for 8 weeks to induce NASH. Caspase-11 expression was determined by (A) reverse-transcription quantitative PCR and (B–D) Western blot, respectively. n = 5 for control group, n = 8 for MCD group. ∗∗∗∗P < .0001.
