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. 2021 Jun 23;13:670463. doi: 10.3389/fnagi.2021.670463

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Copyright © 2021 Cao, Nie, Zhang, Chen, Wang, Liu, Mo, Du, Hu, Tian, Wei and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences of functional connectivity (FC) between groups at the right-sided cerebellum lobule VI—whole brain level. (A) Significant differences were observed between patients with WMHs and healthy controls (HC) in the FC between the right-sided cerebellum lobule VI with the left anterior cingulate gyri (voxel size: 39; peak MNI coordinates: x = –3, y = 33, and z = –6; GRF for voxel levels at P < 0.001 and cluster at P < 0.05). (B) The functional connectivity of the right-sided cerebellum lobule VI with the left anterior cingulate gyri was significantly decreased in patients with WMHs. ^∗∗∗P < 0.001.