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Ferrous-supply-regeneration nanosystems for acid-responsive and imaging-guided tumor therapy. (A) Schematic illustration of the sorafenib-mediated combination of ferroptosis and PDT. (B) Sorafenib and MB release profiles at different pH conditions. (C) Iron release profiles at different pH conditions. (D) In vivo biodistribution of tumor-bearing mice after administration of SFT-MB. Adapted with permission from [85]. Copyright 2018, American Chemical Society.
