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Chitosan and lactobionic acid dual-functionalized mesoporous silica nanoparticles (MSN) for simultaneous drug delivery. (A) Schematic diagram of the preparation of dual-functionalized MSN. (B) Schematic illustration of the synergistic effect induced by the dual-functionalized MSN. (C) Visual illustration of tumor sizes after different treatments. (D) Time-dependent growth curves after different treatments. Adapted with permission from [33], Copyright 2017, Elsevier.
