Fig. 11.

Self-imaging and self-delivered nanodrugs for sorafenib and ICG co-delivery. (A) Schematic illustration of the sorafenib-mediated combination of chemotherapy and self-imaging-guided PDT. (B) In vivo biodistribution of tumor-bearing mice after administration of SINP and free ICG. (C) Ex vivo fluorescent images of tumors after 2, 6, 12, and 24 h of administration. (D) Time-dependent growth curves, average tumor weights and overall survival curve of mice after different treatments. (E) Visual illustration of tumor sizes after different treatments. Adapted with permission from [123]. Copyright 2019, American Chemical Society.