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. 2021 Jun 23;12:674616. doi: 10.3389/fendo.2021.674616

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Copyright © 2021 Guo, Chen, Li, Li, Shen, Gan, Feng, Cai, Liu and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The prognostic value of TMB and its correlation with risky clinical features. (A) The association between TMB and recurrence-free survival rate. (B) Correlation between TMB and age. (C) Correlation between TMB and gender. (D) Correlation between TMB and AJCC-T staging. (E) Correlation between TMB and AJCC-N staging. (F) Correlation between TMB and AJCC-M staging. (G) Correlation between TMB and tumor staging. (H) Correlation between TMB and histopathology. (I) Correlation between TMB and BRAF status. (J) Confirming the predictive value of TMB and risky clinical features through the ROC curve.