Fig. 5.

(A) Preparation routine of single-membrane and double-membrane microsphere hydrogels; optical microscope images of (B) the SA/CCNC single-membrane microsphere hydrogel, (C) the SA/CCNC-1 h double-membrane microsphere hydrogel. Complexing drug release study involving ceftazidime hydrate (CH, the open symbols) and epidermal growth factor human (EGF, the solid symbols) of the double-membrane hydrogels in the pH 7.4 buffer solution (D) drug release profiles, (E) UV spectra of CH release for the SA/CCNC-1 h double-membrane hydrogel at the critical times, and (F) UV spectra of EGF release for the SA/CCNC-1 h double membrane hydrogel with the Bradford method at the critical times. Adapted with permission from [144]. Copyright (2016), American Chemical Society.