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. 2021 Jun 24;13:680205. doi: 10.3389/fnagi.2021.680205

Table 1.

Sensitive analyses of association between aortic PWV and cognitive function.

Outcomes Analysis 1 Analysis 2 Analysis 3 Analysis 4
Studies Participants r (95% CI) Studies Participants r (95% CI) Studies Participants r (95% CI) Studies Participants r (95% CI)
Attention 9 5,198 −0.174 (−0.313, −0.027)* 7 5,041 0.006 (−0.051, 0.063) 5 4,335 0.031 (−0.009, 0.071) 4 4,279 0.034 (−0.012, 0.079)
Executive Function 13 10,070 −0.051 (−0.118, 0.017) 11 9,913 −0.006 (−0.061, 0.050) 9 9,207 0.017 (−0.043, 0.076) 8 9,151 0.003 (−0.054, 0.059)
Global cognitive function 6 1,999 −0.122 (−0.218, −0.024)* 6 1,999 −0.122 (−0.218, −0.024)* 4 1,293 −0.113 (−0.255, 0.034) 3 1,127 −0.055 (−0.143, 0.033)
Memory 14 12,328 −0.061 (−0.101, −0.020)* 12 12,171 −0.034 (−0.063, −0.004)* 10 11,465 −0.022 (−0.041, −0.003)* 9 11,409 −0.022 (−0.042, −0.001)*
Processing speed 13 8,775 −0.119 (−0.190, −0.047)* 11 8,618 −0.056 (−0.094, −0.017)* 10 8,476 −0.048 (−0.081, −0.016)* 9 8,420 −0.048 (−0.082, −0.014)*
Visuospatial ability 5 1,280 −0.085 (−0.300, 0.140) 5 1,280 −0.085 (−0.300, 0.140) 4 1,138 −0.073 (−0.328, 0.192) 4 1,138 −0.073 (−0.328, 0.192)

Analysis 1 included all the eligible studies; Analysis 2 excluded studies with participant of chronic kidney disease based on analysis 1; Analysis 3 further excluded studies with participants of hypertension based on analysis 2; Analysis 4 further excluded studies with participants complaining loss of memory based on analysis 3 and just included studies with participants from general older adults.

*

P < 0.05.